IS YOUR LIFE KILLING YOU?

IS YOUR LIFE KILLING YOU?

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Posted on: January 14, 2017

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A tight deadline at work, sitting in traffic, falling behind in responding to emails… We all experience stress from time to time. But what happens when that stress becomes constant rather than occasional? This persistent exposure to stress over a long period of time is known as chronic stress, and it can lead to health problems like anxiety, insomnia, and high blood pressure. Chronic stress can also contribute to the development of serious illnesses like heart disease and depression—particularly if you’re already genetically predisposed to these issues. According to some studies, the overeating of “comfort foods” in an attempt to manage chronic stress may even be partially responsible for the current obesity epidemic. Other research suggests a link between stress (both acute and chronic) and vulnerability to addiction.

Chronic stress can also damage your brain. In 2014, researchers at the University of California-Berkeley determined that long term changes in brain function are triggered by chronic stress. These findings might help explain why people exposed to chronic stress when they’re young are more susceptible to mental health issues like anxiety and mood disorders later in life.

Why is chronic stress so bad for us? The body’s stress response evolved to protect against predators. A perceived attack causes the release of stress hormones like adrenaline and cortisol as we prepare to defend ourselves, hearts pumping. Usually this fight-or-flight response regulates itself, and our hormone levels and blood pressure return to normal once the threat has passed. But what when the “threat” is actually the constant worry over making ends meet or toiling under a heavy workload, our stress response system is forced to stay on all the time. This overuse causes other body systems to deregulate and, eventually, break down.

Top 5 Chronic Stress Solutions

Eat less sugar

Sleep more

Exercise

Yoga, meditation, Tai Chi or journaling

Make a plan to do something you enjoy

Now that you know how harmful chronic stress can be, what can you do to prevent it? You might not be able to avoid the things in your life that cause you stress, but you can control how you react to them. You have the power to reduce your stress levels by making positive lifestyle choices. Basic things like eating well and getting enough rest can have a big impact. Make some non-instant oatmeal for breakfast instead of your usual sugary cereal. Power down your laptop and go to bed at a decent hour every night. As a physician who also competes in triathlons, I’m a huge believer in the power of exercise to relieve stress. (And I’m not the only one—check out my post here  to learn about some of the latest research on this topic.) Relaxation techniques like yoga and meditation have also been scientifically proven to lower stress levels. Even giving yourself permission to spend time doing something you love, whether it’s reading comic books or watching stand-up, can help you blow off steam. Whatever relaxation method you choose, the important thing is to make a plan and stick to it. Take charge of your stress so you can stop worrying and focus on achieving your goals.

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RUN IT OUT

RUN IT OUT

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Posted on: December 23, 2016

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…or Cycle or Swim or Lift It Out

 

Stressed out? You’re not the only one. In a 2014 poll conducted by NPR with the Robert Wood Johnson Foundation and the Harvard School of Public Health, more than 1 in 4 Americans reported having a lot of stress in the past month, while 50% of respondents—over 115 million people—said they experienced a stressful event in the last year. Considering that polls like this one don’t count the hidden, unconscious stress people experience without knowing it, it’s pretty clear we’re dealing with a serious and pervasive problem. Fortunately, one of the best and most immediate ways to beat stress is also one of the simplest: exercise.

 

In addition to physically affecting your body, exercise chemically alters your brain. Not only does it boost production of endorphins—the neurotransmitters responsible for that “runner’s high” you get after working out—exercise also lowers levels of stress hormones like cortisol and adrenaline. One study conducted at Princeton and published in the Journal of Neuroscience shows physical activity can even reorganize your brain so it responds less to stress. Mice in the study were divided into two groups, one with free access to a running wheel and one without a wheel. After six weeks, the mice were  briefly exposed to a stressor in the form of cold water. Right after the stressor, the brains of the active mice experienced an activity jump in neurons responsible for shutting down excitement in the part of the brain, the ventral hippocampus, known to regulate anxiety. At the same time, neurons in the runner mice released more gamma-aminobutyric acid (GABA), a neurotransmitter that calms nerve activity in the brain.

 

I like running alone, but in exercise can provide you with an ideal opportunity to network or spend time with friends. If you’re like me, it also provides a great excuse to have some “Me” time.  Exercise also acts to lessen stress on a behavioral level. As you start to see changes in your body—from weight loss to increased strength and stamina—your confidence will grow accordingly. Suddenly more vigorous and energetic, you’ll have the power and self-discipline necessary to accomplish all your goals rather than stressing over them.

 

Excercise

 

I know you’re thinking you’re too busy to exercise, especially since you probably need to spend a billion hours at the gym to reap any stress-busting benefits. After all, your lack of spare time is probably one of the things that’s stressing you out. But you really only need to do a little bit—twenty minutes or so—every day to take the edge off. Instead of scrolling through social media over lunch, try taking a quick walk around the block, which some research has shown to have the same effect as a mild tranquilizer. (Since exercise also improves your focus and concentration, you’ll be more relaxed AND super sharp for that afternoon meeting.) In the evening, spend some time watching TV on the treadmill instead of the couch. Take it from a busy physician who’s also a triathlete—you’ll never regret making time to exercise. And alleviating some of your stress allows you to be the best, most successful version of yourself. Why settle for anything less?

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THE MOST STRESSFUL TIME OF THE YEAR

THE MOST STRESSFUL TIME OF THE YEAR

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Posted on: December 3, 2016

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Do the holidays and post-election happenings have you stressed out?

If you’re so stressed out you feel like it’s affecting your health, you’re probably right. Chronic stress has been linked to conditions like heart disease, anxiety, diabetes, and depression. We’ve all been told we need to lower our stress levels, but who has the time? Is there a simple way to relax that actually works? Consider mindfulness meditation. Just a few minutes of contemplation every day has been shown to reduce stress, improve attention, and much more.

Don’t forget that the most proven, accessible and useful tool is available for you to start and use at any time – meditation. 

Put simply, mindfulness means focusing on the present. According to Jon Kabat-Zinn, who created a program called mindfulness-based stress reduction (MSBR) that has brought meditation into the mainstream, mindfulness involves paying deliberate, nonjudgmental attention to the moment. This neutral mindset helps us see our worries and concerns for what they are—just thoughts—and allows us to let them go. In a study conducted by Dr. Elizabeth Hoge, a psychiatrist at the Center for Anxiety and Traumatic Stress Disorders at Massachusetts General Hospital and an assistant professor of psychiatry at Harvard Medical School, people with generalized anxiety who followed a stress-reduction program based on mindfulness were considerably less anxious than those in a control group who were taught other stress management techniques. Another study found health care professionals who participated in an MSBR program reported significantly less stress and more self-compassion compared to a control group. Researchers have even found mindfulness to be helpful in treating serious mental health issues like obsessive compulsive disorder and drug addiction.

 

For those of you wanting more tangible proof of meditation’s benefits, consider this: mindfulness actually changes your brain. Sara Lazar, a neuroscientist at Harvard Medical School and Massachusetts General Hospital, conducted studies involving brain scans of meditators. She found that people who had been meditating for a long time had increased grey matter in the auditory and sensory cortex, which she attributes to the mindful attention paid to breathing, sounds, and other stimuli during meditation. She also discovered more grey matter in the frontal cortex, the part of the brain associated with memory and decision making. According to Lazar, meditators in their fifties had the same amount of gray matter in one part of the prefrontal cortex as people in their twenties in spite of the fact that the cortex is known to shrink as we age.

santa-medit

Not only does meditation cause concrete change, it can do so relatively quickly. While Lazar’s initial study looked at long-term meditators, subsequent research showed increases in subjects’ brain volume after just eight weeks of meditation. Another study by J. David Creswell and his team at Carnegie Mellon University and published in the June 2014 issue of Psychoneuroendocrinology looked at whether “low doses” of meditation would affect stress response. When completing nerve-wracking tasks assigned to them, participants who received just three days of 25-minute mindfulness training sessions reported lower perceived stress levels than a control group.

 

The takeaway? Even if you’re short on time (and who isn’t?) you can reap the substantial stress-busting benefits of mindfulness meditation. Many guided meditations are available online for free, and you can even download apps like Stop, Breathe, & Think that allow you to sample the basics of mindfulness.

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NEUROPLASTICITY

NEUROPLASTICITY

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Posted on: October 15, 2016

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When it comes to your brain, you actually can teach an old dog new tricks. Once thought to be hard-wired after early childhood, the brain actually has a remarkable ability to change and heal itself. Known as neuroplasticity, this remodeling due to our environment, behavior, and feelings happens throughout our whole lives.

 

For many years, scientists thought of the human brain as a kind of machine doomed to break down over time. But in the 1970s, studies began to show the brain rewiring itself according to experience. At the University of California-San Francisco, Dr. Michael Merzenich found that the area of the brain responsible for processing sensory input from a body part weakened or was assigned another function if an animal stopped using that body part. Dr. Mark Rosenzweig and his colleagues at the University of California-Berkeley discovered animals’ brains grew in key areas with environmental stimulation. The results of both of these studies have been replicated many times, and current research offers further evidence of the brain’s plasticity.

 

Physical Exercise Improves Brain Function: Plasticity at its finest

brain-exercise

A 2013 review conducted by Kirk Erickson and his team at the University of Pittsburgh and published in the Proceedings of the National Academy of Sciences found significant growth of the hippocampus, the part of the brain linked to memory, in people who exercised aerobically for one year.  Across many studies reviewed, people who exercise more had improved cognitive function

What does all this science suggest? If the brain is malleable, can it be trained?

 

Many experts think so.

Meditators have larger pre-frontal cortex sizes, the part of the brain important in executive decision-making.  And brain scans done on stroke patients treated by Edward Taub, a neuroscientist at the University of Alabama-Birmingham who helps people recover the use of their limbs by putting the “good” arm in a sling and methodically retraining the paralyzed arm, have shown healthy neurons taking over for adjacent damaged ones.

In The Woman Who Changed Her Brain: How I Left My Learning Disability Behind and Other Stories of Cognitive Transformation, Barbara Arrowsmith-Young details her own experience with neuroplasticity. Born with severe learning disabilities, Arrowsmith-Young made it all the way to graduate school through intense willpower. Her research there inspired her to develop a set of cognitive exercises for herself, and she’s spent the last 30 years sharing her work with kids and adults at her Arrowsmith Schools. (See Arrowsmith-Young’s TED Talk here.) Another believer, psychiatrist and researcher Norman Doidge, wrote a book, The Brain That Changes Itself, about neuroplasticity and the ways in which people can harness it to increase their mental and even physical strength.

According to the afore-mentioned plasticity research pioneer Dr. Merzenich, though, certain conditions are important to help maximize your brain’s flexibility. He lists several core principles necessary for training your brain in his book, Soft-Wired: How the New Science of Brain Plasticity Can Change Your Life. These necessities include engagement and motivation, a strong desire to master something, and dedicated practice. Merzenich also describes the brain as “use it or lose it” and warns it’s as easy to affect a negative brain change as it is a positive one.

The bottom line is, you’re not stuck with the brain you were born with. Through focused perseverance, you can harness the power of neuroplasticity.

Tack180 incorporates an understanding of such neuroplasticity in the individualize optimal health plan every Tack180 client receives – Tack180 helps you rewire your brain toward achieving your goals.

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PURPOSE

PURPOSE

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Posted on: September 22, 2016

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Purpose and Death

Did you know having a sense of purpose can actually add years to your life? An analysis of ten studies following 136,000 people from the United States and Japan for around seven years found those who reported a feeling of higher purpose in life lowered their risk of death during the study period by approximately 20 percent. The study, published in the Dec. 3 2015 issue of Psychosomatic Medicine: Journal of Biobehavioral Medicine also found participants who said their lives were meaningful had less chance of developing heart disease. Although it’s not clear exactly how a sense of purpose can lengthen life, the authors of this particular study think it might protect the body from potentially harmful stress responses as well as encourage a generally healthier lifestyle. And while the study shows an association rather than a cause and effect relationship, its implication—that knowing what you want out of life and having a plan to get it can impact lifespan—is significant.

Making a Plan

So let’s say you take this research about a sense of purpose to heart and make a goal for yourself. How do you achieve it? First and foremost, set and declare a clear intention. A study published in the British Journal of Health Psychology measured how often people exercised over two weeks. Researchers randomly divided 248 people into three groups. In the control group, participants were asked to keep track of how often they exercised and then instructed to read a few paragraphs of a novel. In addition to being asked to track exercise, the second group read a pamphlet on the benefits of exercise for reducing heart disease and given a motivational speech. The third group was told to track their exercise and given the same pamphlet and speech as the second group, but they were also asked to come up with a plan explicitly stating where and when they intended to exercise. At the end of the two-week study period, only 38% of people in the control group and 35% of the second group exercised at least once a week. In the third group, where participants wrote down exactly what they planned to do? A whopping 91% of this group exercised at least once a week. By simply setting and stating a clear intention, you can seriously amp up your chances of achieving your goal.

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EXERCISE

EXERCISE

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FIX YOUR BRAIN

Every day I have patients who come to me asking what they should take to help prevent memory loss or to treat depression or “brain fog” – a loss of ability to concentrate fully. Though people often come to me looking for a magic pill, there is one prescription that is more proven, consistently helpful and accessible than any pill, prescription, or over-the- counter supplement. It’s called EXERCISE. It turns out that aerobic exercise slows the loss of gray matter- the part of the brain that atrophies as we age. This is just one way in which exercise keeps us mentally young. Scientists have found that anaerobic exercise, such as working out with weights, also stimulates the creation of new brain cells in the part of the brain responsible for memory and learning – the dentate gyrus (part of the hippocampus).

NEUROPLASTICITY

Many people think that the brain stops growing by adulthood, but new nerve cells continue to be generated in the hippocampus throughout our lives. Exercise can help stimulate the growth of such cells, which are essential to learning and memory. In fact, a recent study showed that aerobic exercise increases levels of two neurotransmitters, GABA and glutamate, low levels of which are associated with depression. Other studies have shown actual expansion of gray matter after regular exercise.

PREVENT DEMENTIA

It is well established that exercise reduces the risk of heart disease and stroke, both of which are associated with dementia. One recent study from the Journal of Alzheimer’s Disease showed that any type of exercise, including gardening, walking or biking decreased risk of Alzheimer’s by a whopping 50%, even without regard to impact on heart disease or stroke.

People spend enormous resources investigating and purchasing supplements that have far less evidence supporting their use in preventing neurological decline than does simple exercise. Staying physically active can help your brain stay active too!

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EPIGENETICS

EPIGENETICS

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If you think genetic predisposition means certain conditions are inevitable, think again. Far from being at the mercy of your genes, you can affect which ones are turned on and off—not just in yourself but in your children and grandchildren—through lifestyle choices like diet, exercise, and stress management. The ever-expanding field of epigenetics, the study of how chemical and environmental factors impact our genetic health, has revealed many ways in which we can influence our genes. One study found people who ate more fruits and vegetables were less likely to develop cardiovascular disease even if they carried copies of the gene that increases risk of heart problems, effectively “turning off” the gene.

switch

Research has also shown exercise can cause certain stem cells to differentiate into bone and blood cells instead of fat cells. In another experiment where male mice were taught through electric shock to fear the smell of fruit, not only did the mice grow extra neurons in their noses and brains to heighten their sensitivity to the scent, their babies were born fearing the smell and with the same extra neurons. By instilling fear in the father mice, scientists altered the way genetic code instructions were translated, and the baby mice inherited a trait learned by their parents through experience. The genetic sequence itself doesn’t change, but epigenetic changes can be passed on to the next generation.

Methylation?

And if you’ve heard the term “methylation” tossed around lately, it’s because this biochemical process of adding (or subtracting, also known as demethylation) a methyl group to DNA can act as an on/off switch for genes, and it may happen in response to environmental factors. A study of people with stomach cancer showed participants could affect methylation of an important gene by drinking green tea and eating cruciferous vegetables. The upshot of all this science? The power to control your genetic health is, to an extent, in your hands if you’re willing to be proactive about lifestyle changes like eating well, exercising, and managing stress. Just because your grandfather and father suffered a certain fate doesn’t mean you will, too.

I will be writing much more on epigenetics in posts to come. Consider this a quick intro, because our ability to turn on and off genes is one of the most exciting and relevant discoveries there has ever been.

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